7-Fluorotryptamine (hydrochloride)

7-Fluorotryptamine hydrochloride is a potent agonist of GPRC5A. 7-Fluorotryptamine hydrochloride induces GPRC5A-mediated β-arrestin recruitment. 7-Fluorotryptamine hydrochloride can be used for research of immune and cancer signaling[1].

Product Specifications

CAS Number

[159730-09-3]

Product Name Alternative

Setogepram; PBI-4050

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Arrestin

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/7-fluorotryptamine-hydrochloride.html

Concentration

10mM

Purity

98.86

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

NCCC1=CNC2=C(C=CC=C21)F.Cl

Molecular Formula

C10H12ClFN2

Molecular Weight

214.67

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhao X, et al. Chemoproteomics reveals microbiota-derived aromatic monoamine agonists for GPRC5A. Nat Chem Biol. 2023 May 29.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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