9 (R) -HODE
9 (R) -HODE (9 (R) -Hydroxyoctadecadienoic acid) is a monohydroxy fatty acid and metabolite of linoleic acid. It is formed from linoleic acid by COX and lipoxygenase (LO) .9 (R) -HODE induces chemotaxis, increases the levels of chemokine (C-C motif) receptor 9 (CCR9) and chemokine (C-X-C motif) receptor 4 (CXCR4), and inhibits IL-6 release in primary human monocytes. It inhibits CD3α- and CD28-induced proliferation of isolated human peripheral blood lymphocytes when used at a concentration of 25 μg/mL.
Product Specifications
CAS Number
10075-11-3
Product Name Alternative
9 (R) -Hydroxyoctadecadienoic acid
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/9-r-hode.html
Smiles
CCCCC/C=C\C=C\[C@H](O)CCCCCCCC(O)=O
Molecular Formula
C18H32O3
Molecular Weight
296.44
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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