Propargyl-C2-NHS ester

Propargyl-C2-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC) . Propargyl-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[906564-59-8]

UNSPSC

12352203

Hazard Statement

H315, H319

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/propargyl-c2-nhs-ester.html

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C#CCCCC(ON1C(CCC1=O)=O)=O

Molecular Formula

C10H11NO4

Molecular Weight

209.20

Precautions

H315, H319

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Non-cleavable Linker

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS6275256-01 0.1 mL

ARMC5, CT (ARMC5, Armadillo repeat-containing protein 5) (MaxLight 650)

Ask

View Details

MBS6275256-02 5x 0.1 mL

ARMC5, CT (ARMC5, Armadillo repeat-containing protein 5) (MaxLight 650)

Ask

View Details

NBP3-00293R 0.1 mL

Rabbit Polyclonal Dystroglycan Antibody [DyLight 550]

Ask

View Details

RC204112 10 µg

TEM8 (ANTXR1) (NM_018153) Human Tagged ORF Clone

Ask

View Details

NBP3-26081AF532 0.1 mL

Rabbit Polyclonal PPP1R3C Antibody [Alexa Fluor 532]

Ask

View Details