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Hidrosmin

Hidrosmin, a flavonoid, is derived from Diosmin. hidrosmin exerts a beneficial effect against diabetic nephropathy (DN) by reducing inflammation, oxidative stress, and senescence pathways. Hidrosmin can be used for the research of venous insufficiency and diabetes mellitus[1].

Product Specifications

CAS Number

115960-14-0

UNSPSC

12352005

Target

Interleukin Related; NADPH Oxidase

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/hidrosmin.html

Smiles

OCCOC1=C2C(OC(C3=CC(O)=C(C=C3)OC)=CC2=O)=CC(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)O)O)O)=C1

Molecular Formula

C30H36O16

Molecular Weight

652.60

References & Citations

[1]Jiménez-Castilla L, et al. Nephroprotective Effects of Synthetic Flavonoid Hidrosmin in Experimental Diabetic Nephropathy. Antioxidants (Basel) . 2021 Nov 29;10 (12) :1920.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

IL-1; NOX1; NOX4

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