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7-Chloro-4- (piperazin-1-yl) quinoline

7-Chloro-4- (piperazin-1-yl) quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4- (piperazin-1-yl) quinolone is apotent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM) . 7-Chloro-4- (piperazin-1-yl) quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively.

Product Specifications

CAS Number

837-52-5

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 50 mg/mL (201.84 mM; Ultrasonic)

Smiles

ClC1=CC2=NC=CC (N3CCNCC3) =C2C=C1

Molecular Formula

C13H14ClN3

Molecular Weight

247.72

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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