1-Phenylbiguanide HCl
Compound PDK0269, as 5-HT3 receptor agonists (3–100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts/episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%) . When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited.
Product Specifications
CAS Number
55-57-2
Purity
>98% (HPLC)
Smiles
Cl.NC (N) =NC (=N) NC1=CC=CC=C1
Molecular Formula
C8H12ClN5
Molecular Weight
213.67
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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