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AG-825

AG-825 (Tyrphostin AG-825) is a selective and ATP-competitive ErbB2 inhibitor which suppresses tyrosine phosphorylation, with an IC50 of 0.35 μM. AG-825 displays anti-cancer activity.AG825 significantly accelerates apoptosis of human neutrophils. AG-825 is a potential agent for overcoming Mn-induced neurotoxicity or AD development.

Product Specifications

CAS Number

149092-50-2

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 250 mg/mL (628.98 mM; Ultrasonic)

Smiles

COc1cc (\C=C (/C#N) C (N) =O) cc (CSc2nc3ccccc3s2) c1O

Molecular Formula

C19H15N3O3S2

Molecular Weight

397.47

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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