Aphidicolin
Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
Product Specifications
CAS Number
38966-21-1
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (147.72 mM)
Smiles
[H][C@]12C[C@]3 ([H]) C[C@]1 (CC[C@]3 (O) CO) [C@@]1 (C) CC[C@@H] (O) [C@@] (C) (CO) [C@]1 ([H]) CC2
Molecular Formula
C20H34O4
Molecular Weight
338.48
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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