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Bromoenol lactone

Bromoenol lactone ((6E) -Bromoenol lactone) is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A2 (iPLA2β) with an IC50 value of approximately 7 μM, which inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx.

Product Specifications

CAS Number

88070-98-8

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 50 mg/mL (157.64 mM; Ultrasonic)

Smiles

O=C1C (C=2C3=C (C=CC2) C=CC=C3) CC/C (=C\Br) /O1

Molecular Formula

C16H13BrO2

Molecular Weight

317.18

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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