Canagliflozin hemihydrate
Canagliflozin hemihydrate (JNJ28431754 hemihydrate) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively.
Product Specifications
CAS Number
928672-86-0
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : ≥ 100 mg/mL (220.50 mM)
Smiles
O[C@H]1[C@H] (C2=CC (CC3=CC=C (C4=CC=C (C=C4) F) S3) =C (C=C2) C) O[C@@H] ([C@H] ([C@@H]1O) O) CO.O[C@H]5[C@H] (C6=CC (CC7=CC=C (C8=CC=C (C=C8) F) S7) =C (C=C6) C) O[C@@H] ([C@H] ([C@@H]5O) O) CO.O
Molecular Formula
C48H52F2O11S2
Molecular Weight
907.05
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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