(Rac) -MEM 1003

(Rac) -MEM 1003 is the racemate of MEM 1003. MEM 1003, a dihydropyridine compound, is a potent L-type Ca2+ channel antagonist and has the potential for Alzheimer’s disease research[1].

Product Specifications

CAS Number

[165187-25-7]

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/rac-mem-1003.html

Purity

99.64

Solubility

DMSO : 125 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

O=C(OCCOC)C1=C(NC(C)=C(C1C2=CC=CC(C#N)=C2Cl)C(OC(C)C)=O)C

Molecular Formula

C22H25ClN2O5

Molecular Weight

432.90

References & Citations

[1]Gregory M Rose, et al. Efficacy of MEM 1003, a novel calcium channel blocker, in delay and trace eyeblink conditioning in older rabbits. Neurobiol Aging. 2007 May;28 (5) :766-73.