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Pamoic acid disodium

Pamoic acid disodium is a potent GPR35 agonist with an EC50 value of 79 nM. Pamoic acid disodium induces GPR35 internalization and activates ERK1/2 with EC50 values of 22 nM and 65 nM, respectively. Pamoic acid disodium potently recruits β-arrestin2 to GPR35 and has an antinociceptive effect.

Product Specifications

CAS Number

6640-22-8

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 100 mg/mL (231.30 mM; Ultrasonic (<60°C)

Smiles

[Na+].[Na+].Oc1c (cc2ccccc2c1Cc1c (O) c (cc2ccccc12) C ([O-]) =O) C ([O-]) =O

Molecular Formula

C23H16NaO6

Molecular Weight

411.36

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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