XY018
XY018 is a potent ROR-γ-selective antagonist. XY018 inhibits ROR-γ constitutive activity in 293T cells with high potency (EC50, 190 nM) . XY018 binds to the ROR-γ hydrophobic ligand binding domain (LBD) .
Product Specifications
CAS Number
1873358-87-2
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (193.66 mM; Ultrasonic)
Smiles
O=C (CC1=C ([N+] ([O-]) =O) C=CC=C1) NC2=CC=C (C3=CC=C (C (C (F) (F) F) (C (F) (F) F) O) C=C3F) C=C2
Molecular Formula
C23H15F7N2O4
Molecular Weight
516.37
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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