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Remogliflozin etabonate

Remogliflozin etabonate (GSK189075) is an orally active, selective and low-affinity sodium glucose cotransporter (SGLT2) inhibitor with Ki values of 1.95 μM, 2.14 μM, 43.1 μM, 8.57 μM for hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectively. Remogliflozin etabonate is a proagent based on benzylpyrazole glucoside and is metabolized to its active form, Remogliflozin, in the body. Remogliflozin etabonate exhibits antidiabetic efficacy in rodent models.

Product Specifications

CAS Number

442201-24-3

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 100 mg/mL (191.35 mM; Ultrasonic)

Smiles

CCOC (=O) OC[C@H]1O[C@@H] (Oc2nn (C (C) C) c (C) c2Cc2ccc (OC (C) C) cc2) [C@H] (O) [C@@H] (O) [C@@H]1O

Molecular Formula

C26H38N2O9

Molecular Weight

522.59

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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