Nefopam-d3
Nefopam-d3 is a deuterium labeled Nefopam (Fenazoxine) . Nefopam is a centrally-acting but non-opioid analgesic drug, and Nefopam targets β-catenin protein level in mesenchymal cells[1][2].
Product Specifications
CAS Number
1346747-15-6
Product Name Alternative
Fenazoxine-d3
UNSPSC
12352005
Target
β-catenin
Type
Isotope-Labeled Compounds
Related Pathways
Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])N1CCOC(C2=CC=CC=C2)C3=CC=CC=C3C1
Molecular Formula
C17H16D3NO
Molecular Weight
256.36
References & Citations
[1]Kim KH, et al. Rediscovery of nefopam for the treatment of neuropathic pain. Korean J Pain. 2014 Apr;27 (2) :103-11.|[2]Baht GS, et al. Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair. Bone. 2017 May;98:31-36.|[3]Poon R, et al. A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders. PLoS One. 2012;7 (5) :e37940.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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