Dehydro Nifedipine
Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.
Product Specifications
CAS Number
67035-22-7
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Smiles
COC (=O) c1c (C) nc (C) c (C (=O) OC) c1-c1ccccc1[N+] ([O-]) =O
Molecular Formula
C17H16N2O6
Molecular Weight
344.32
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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