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Dehydro Nifedipine

Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.

Product Specifications

CAS Number

67035-22-7

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Smiles

COC (=O) c1c (C) nc (C) c (C (=O) OC) c1-c1ccccc1[N+] ([O-]) =O

Molecular Formula

C17H16N2O6

Molecular Weight

344.32

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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