Ac-FLTD-CMK
Ac-FLTD-CMK, a gasdermin D (GSDMD) -derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 μM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3.
Product Specifications
CAS Number
2376255-48-8
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (175.73 mM; Ultrasonic)
Smiles
CC (C) C[C@H] (NC (=O) [C@H] (Cc1ccccc1) NC (C) =O) C (=O) N[C@@H] ([C@@H] (C) O) C (=O) N[C@@H] (CC (O) =O) C (=O) CCl
Molecular Formula
C26H37ClN4O8
Molecular Weight
569.05
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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