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Ac-FLTD-CMK

Ac-FLTD-CMK, a gasdermin D (GSDMD) -derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 μM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3.

Product Specifications

CAS Number

2376255-48-8

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 100 mg/mL (175.73 mM; Ultrasonic)

Smiles

CC (C) C[C@H] (NC (=O) [C@H] (Cc1ccccc1) NC (C) =O) C (=O) N[C@@H] ([C@@H] (C) O) C (=O) N[C@@H] (CC (O) =O) C (=O) CCl

Molecular Formula

C26H37ClN4O8

Molecular Weight

569.05

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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