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Naphthofluorescein

Naphthofluorescein inhibits the interaction between HIF-1 and Mint3.Naphthofluorescein suppresses Mint3-dependent HIF-1 activity and glycolysis in cancer cells and macrophages without cytotoxicity in vitro and adverse effect in vivo. Naphthofluorescein is also a fluorescent pH-sensitive probe that can be used for functional Cerenkov imaging.

Product Specifications

CAS Number

61419-02-1

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 125 mg/mL (289.07 mM; Ultrasonic)

Smiles

Oc1ccc2c3Oc4c (ccc5cc (O) ccc45) C4 (OC (=O) c5ccccc45) c3ccc2c1

Molecular Formula

C28H16O5

Molecular Weight

432.42

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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