Naphthofluorescein
Naphthofluorescein inhibits the interaction between HIF-1 and Mint3.Naphthofluorescein suppresses Mint3-dependent HIF-1 activity and glycolysis in cancer cells and macrophages without cytotoxicity in vitro and adverse effect in vivo. Naphthofluorescein is also a fluorescent pH-sensitive probe that can be used for functional Cerenkov imaging.
Product Specifications
CAS Number
61419-02-1
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 125 mg/mL (289.07 mM; Ultrasonic)
Smiles
Oc1ccc2c3Oc4c (ccc5cc (O) ccc45) C4 (OC (=O) c5ccccc45) c3ccc2c1
Molecular Formula
C28H16O5
Molecular Weight
432.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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