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Z62954982

Z62954982 (ZINC08010136) is a potent, selective and cell-permeable Rac1 (IC50=12 μM) inhibitor that is 4 times more effective than NSC23766 (HY-15723A) (IC50=50 μM) . Z62954982 disrupts the Rac1/Tiam1 complex and decreases cytoplasmic levels of active Rac1 (GTP-bound Rac1), without affecting the activity of other Rho GTPases (such as Cdc42 or RhoA) .

Product Specifications

CAS Number

1090893-12-1

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 14.29 mg/mL (34.40 mM; Ultrasonic)

Smiles

O=C (NC1=CC=C (C (=C1) S (=O) (=O) N) C) C=2C=CC=C (OCC=3C (=NOC3C) C) C2

Molecular Formula

C20H21N3O5S

Molecular Weight

415.46

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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