PERK-IN-4
PERK-IN-4 is a potent and selective PERK (protein kinase R (PKR) -like endoplasmic reticulum kinase) inhibitor with an IC 50 of 0.3 nM. PERK is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states.
Product Specifications
CAS Number
1337531-89-1
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 20.83 mg/mL (44.37 mM; Ultrasonic)
Smiles
Cn1cc (-c2ccc3N (CCc3c2) C (=O) Cc2cc (F) cc (c2) C (F) (F) F) c2c (N) ncnc12
Molecular Formula
C24H19F4N5O
Molecular Weight
469.43
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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