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Atuzabrutinib

Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor. Atuzabrutinib inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling.

Product Specifications

CAS Number

1581714-49-9

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 100 mg/mL (185.32 mM; Ultrasonic)

Smiles

NC1=C2C (N (N=C2C3=C (F) C=C (OC4=CC=CC=C4) C=C3) [C@H]5CN (C (/C (=C/C (C) (C) C) /C#N) =O) CCC5) =NC=N1

Molecular Formula

C30H30FN7O2

Molecular Weight

539.6

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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