Atuzabrutinib
Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor. Atuzabrutinib inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling.
Product Specifications
CAS Number
1581714-49-9
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (185.32 mM; Ultrasonic)
Smiles
NC1=C2C (N (N=C2C3=C (F) C=C (OC4=CC=CC=C4) C=C3) [C@H]5CN (C (/C (=C/C (C) (C) C) /C#N) =O) CCC5) =NC=N1
Molecular Formula
C30H30FN7O2
Molecular Weight
539.6
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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