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SW157765

SW157765 is a selective non-canonical glucose transporter GLUT8 (SLC2A8) inhibitor. KRAS/KEAP1 double mutant NSCLC cells are selectively sensitive to the SW157765, due to the convergent consequences of dual KRAS and NRF2 modulation of metabolic and xenobiotic gene regulatory programs.

Product Specifications

CAS Number

332063-87-3

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 25 mg/mL (75.46 mM; Ultrasonic (<60°C)

Smiles

O=C (Nc1ccc2oc (nc2c1) -c1ccncc1) \C=C\c1ccco1

Molecular Formula

C19H13N3O3

Molecular Weight

331.32

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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