SW157765
SW157765 is a selective non-canonical glucose transporter GLUT8 (SLC2A8) inhibitor. KRAS/KEAP1 double mutant NSCLC cells are selectively sensitive to the SW157765, due to the convergent consequences of dual KRAS and NRF2 modulation of metabolic and xenobiotic gene regulatory programs.
Product Specifications
CAS Number
332063-87-3
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 25 mg/mL (75.46 mM; Ultrasonic (<60°C)
Smiles
O=C (Nc1ccc2oc (nc2c1) -c1ccncc1) \C=C\c1ccco1
Molecular Formula
C19H13N3O3
Molecular Weight
331.32
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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