Obatoclax B
Obatoclax (GX15-070), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a Ki of 220 nM for BCL-2. Obatoclax induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax has anti-cancer and broad-spectrum antiparasitic activity.
Product Specifications
CAS Number
803712-67-6
Purity
>98% (HPLC)
Smiles
C (=C1N=C (C=C1OC) C2=CC=3C (N2) =CC=CC3) C4=C (C) C=C (C) N4
Molecular Formula
C20H19N3O
Molecular Weight
317.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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