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DIF-3

DIF-3 reduces the expression levels of cyclin D1 and c-Myc by facilitating their degradation via activation of GSK-3β. DIF-3 inhibits Wnt/β-catenin signaling pathway-related proteins in DLD-1 cells. DIF-3 exerts a strong antiproliferative effect on the human cervical cancer cell line HeLa by inducing cyclin D1 degradation and inhibiting cyclin D1 mRNA expression.

Product Specifications

CAS Number

113411-17-9

Field of Research

Stem Cell & Developmental Biology

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 100 mg/mL (366.68 mM; Ultrasonic)

Smiles

CCCCCC (=O) c1c (O) cc (OC) c (Cl) c1O

Molecular Formula

C13H17ClO4

Molecular Weight

272.72

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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