DIF-3
DIF-3 reduces the expression levels of cyclin D1 and c-Myc by facilitating their degradation via activation of GSK-3β. DIF-3 inhibits Wnt/β-catenin signaling pathway-related proteins in DLD-1 cells. DIF-3 exerts a strong antiproliferative effect on the human cervical cancer cell line HeLa by inducing cyclin D1 degradation and inhibiting cyclin D1 mRNA expression.
Product Specifications
CAS Number
113411-17-9
Field of Research
Stem Cell & Developmental Biology
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (366.68 mM; Ultrasonic)
Smiles
CCCCCC (=O) c1c (O) cc (OC) c (Cl) c1O
Molecular Formula
C13H17ClO4
Molecular Weight
272.72
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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