AGN 192870
AGN 192870 is a RAR neutral antagonist with Kds of 147, 33, and 42 nM for RARα, RARβ, and RARγ, respectively. AGN 192870 shows IC50s of 87 and 32 nM for RARαand RARγ, respectively. AGN 192870 shows RARβ partial agonism. AGN 192870 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
166977-57-7
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 6.25 mg/mL (16.51 mM; Ultrasonic (<60°C)
Smiles
CC1 (C) C=2C (C (=CC1) C3=CC=CC=C3) =CC (C#CC4=CC=C (C (O) =O) C=C4) =CC2
Molecular Formula
C27H22O2
Molecular Weight
378.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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