SRI-37240
SRI-37240 is a potent premature termination codons (PTCs) inhibitor. SRI-37240 suppresses CFTR nonsense mutations. SRI-37240 alters cellular translation termination at PTCs in HEK293T cells. SRI-37240 can also restore CFTR function in primary bronchial epithelial cells when combination with G418.
Product Specifications
CAS Number
883956-47-6
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 11.36 mg/mL (29.47 mM; Ultrasonic (<60°C)
Smiles
O=C1C=2C=CC=CC2N (C=3N=C (C=4C=CC=CC4) N (C (=O) C13) C5CCCCC5) C
Molecular Formula
C24H23N3O2
Molecular Weight
385.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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