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SRI-37240

SRI-37240 is a potent premature termination codons (PTCs) inhibitor. SRI-37240 suppresses CFTR nonsense mutations. SRI-37240 alters cellular translation termination at PTCs in HEK293T cells. SRI-37240 can also restore CFTR function in primary bronchial epithelial cells when combination with G418.

Product Specifications

CAS Number

883956-47-6

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 11.36 mg/mL (29.47 mM; Ultrasonic (<60°C)

Smiles

O=C1C=2C=CC=CC2N (C=3N=C (C=4C=CC=CC4) N (C (=O) C13) C5CCCCC5) C

Molecular Formula

C24H23N3O2

Molecular Weight

385.46

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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