AMPK-IN-3
AMPK-IN-3 (compound 67) is a potent and selective AMPK inhibitor with IC50s of 60.7, 107 and 3820 nM for AMPK (α2), AMPK (α1) and KDR, respectively. AMPK-IN-3 inhibits AMPK does not affect cell viability or cause significant cytotoxicity in K562 cells. AMPK-IN-3 can be used in study of cancer.
Product Specifications
CAS Number
2417674-27-0
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 115 mg/mL (254.67 mM; Ultrasonic)
Smiles
CCN (CC) CCNC (=O) c1c (C) [nH]c (\C=C2/C (=O) Nc3ccc (CCC (N) =O) cc23) c1C
Molecular Formula
C25H33N5O3
Molecular Weight
451.56
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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