LEM-14
Product Specifications
Product Name Alternative
AZD6140; AR-C 126532XX
UNSPSC Description
LEM-14 is a potent NSD2 inhibitor with an IC50 of 132 µM. LEM-14 has the potential for the research of multiple myeloma[1].
Target Antigen
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lem-14.html
Purity
98.06
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C(C2=C(CCCC2)S3)=C3NC(CN4CCN(C([C@H]5CC6=CC=CC=C6C(O5)=O)=O)CC4)=N1
Molecular Weight
478.56
References & Citations
[1]Shen Y, et al. Identification of LEM-14 inhibitor of the oncoprotein NSD2. Biochem Biophys Res Commun. 2019 Jan 1;508(1):102-108.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114340/LEM-14-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114340/LEM-14-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1814881-70-3
Available Sizes
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