TH1760
TH1760 is an inhibitor of NUDIX-type 15 (NUDT15) with an IC50 value of 25 nM. TH1760 sensitizes cells to 6-thioguanine by enhancing the accumulation of 6-thio- (d) GTP in nucleic acids. TH1760 enhances the anti-leukemia effect of thiopurine.
Product Specifications
CAS Number
2567914-01-4
Purity
>98% (HPLC)
Smiles
S (=O) (=O) (C=1C=C2C (=CC1) NC (=O) O2) N3CCN (C (=O) C=4C=C5C (=CC4) NC=C5) CC3
Molecular Formula
C20H18N4O5S
Molecular Weight
426.45
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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