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USP8-IN-3

USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the proliferation of GH3 and H1957 cells with GI50s of 37.03 μM and 6.01 μM, respectively.

Product Specifications

CAS Number

2477651-10-6

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 100 mg/mL (235.06 mM; Ultrasonic)

Smiles

C (F) (F) (F) C1=NC (=CC=C1) N2CCC (NC (NC3=CC=C (N (=O) =O) C=C3) =S) CC2

Molecular Formula

C18H18F3N5O2S

Molecular Weight

425.43

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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