USP8-IN-3
USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the proliferation of GH3 and H1957 cells with GI50s of 37.03 μM and 6.01 μM, respectively.
Product Specifications
CAS Number
2477651-10-6
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (235.06 mM; Ultrasonic)
Smiles
C (F) (F) (F) C1=NC (=CC=C1) N2CCC (NC (NC3=CC=C (N (=O) =O) C=C3) =S) CC2
Molecular Formula
C18H18F3N5O2S
Molecular Weight
425.43
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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