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GRP78-IN-3

GRP78-IN-3 is a selective Grp78 (HSPA5) inhibitor with an IC50 of 0.59 μM. GRP78-IN-3 is 7-fold selective for HspA5 compared to HspA9 (IC50 of 4.3 μM) and >20-fold selective for HspA5 compared to HspA2 (IC50 of 13.9 μM) .

Product Specifications

CAS Number

2707510-30-1

Field of Research

Cell Biology

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 5 mg/mL (14.60 mM; Ultrasonic)

Smiles

C (N[C@H] (C (NC1=NC=CS1) =O) [C@H] (C) C) (=O) C2=CC=3C (N2) =CC=CC3

Molecular Formula

C17H18N4O2S

Molecular Weight

342.42

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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