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WDR5-0102

WDR5-0102 is an inhibitor targeting WDR5-MLL1 interface (Kdis=7 μM, Kd=4 μM) . WDR5-0102 suppresses MLL1 HMT activity, but not human H3K4 methyltransferase SETD7 and six other HMTs: G9a, EHMT1, SUV39H2, SETD8, PRMT3, and PRMT5.

Product Specifications

CAS Number

824960-50-1

Field of Research

Epigenetics & Chromatin

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 50 mg/mL (133.40 mM; Ultrasonic (<60°C)

Smiles

N (C (=O) C1=C (Cl) C=CC=C1) C2=C (C=CC (N (=O) =O) =C2) N3CCN (C) CC3

Molecular Formula

C18H19ClN4O3

Molecular Weight

374.82

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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