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R 59-022 hydrochloride

R 59-022 (DKGI-I) hydrochloride is a DGK inhibitor (IC50: 2.8 μM) . R 59-022 hydrochloride inhibits the phosphorylation of OAG to OAPA. R 59-022 hydrochloride is a 5-HT Receptor antagonist, and activates protein kinase C (PKC) . R 59-022 hydrochloride potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils.

Product Specifications

CAS Number

93076-98-3

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 25 mg/mL (50.40 mM; Ultrasonic)

Smiles

Cl.O=C1C (=C (N=C2SC=CN21) C) CCN3CCC (=C (C=4C=CC=CC4) C5=CC=C (F) C=C5) CC3

Molecular Formula

C27H27ClFN3OS

Molecular Weight

496.04

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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