NLRP3-IN-13
NLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC50: 2.1 μM) . NLRP3-IN-13 inhibits NLRP3 andNLRC4 inflammasomes, and inhibits NLRP3-mediated IL-1β production. NLRP3-IN-13 also inhibits NLRP3 ATPase activity. NLRP3-IN-13 can be used in the research of neuroinflammatory disorders.
Product Specifications
CAS Number
1704638-35-6
Field of Research
Cell Biology
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (136.83 mM; Ultrasonic)
Smiles
O=C1OC=2C=CC=CC2N1CC (=O) NCC3=CN=CC (=C3) C4=CSC=C4
Molecular Formula
C19H15N3O3S
Molecular Weight
365.41
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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