Carboxylesterase-IN-2
Carboxylesterase-IN-2 (compound 4u) is a potent inhibitor of Carboxylesterase Notum with an IC50 less than or equal to 10 nM. Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity. Carboxylesterase-IN-2 has the potential for the research of cancer disease.
Product Specifications
CAS Number
2764748-88-9
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (183.60 mM; Ultrasonic)
Smiles
O=C1N2C (C=CC (SC3=CC (C) =C (C) C=C3) =N2) =NN1
Molecular Formula
C13H12N4OS
Molecular Weight
272.33
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
