Tyrosine kinase-IN-7
Tyrosine kinase-IN-7 (compound 13h) is an inhibitor of the tyrosine kinase EGFR. The IC50s for inhibiting EGFR (WT) and EGFR (T790M) are 0.630 μM and 0.956 μM respectively. Tyrosine kinase-IN-7 has antitumor activity against four cancer cell lines (HepG2, HCT-116, MCF-7, and A431) with IC50s of 13.02 μM, 10.14 μM, 12.68 μM, and 47.05 μM, respectively.
Product Specifications
CAS Number
345615-74-9
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Smiles
OC1=CC=C (NC2=NC=NC3=C2C2=C (CCCC2) S3) C=C1
Molecular Formula
C16H15N3OS
Molecular Weight
297.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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