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Tyrosine kinase-IN-7

Tyrosine kinase-IN-7 (compound 13h) is an inhibitor of the tyrosine kinase EGFR. The IC50s for inhibiting EGFR (WT) and EGFR (T790M) are 0.630 μM and 0.956 μM respectively. Tyrosine kinase-IN-7 has antitumor activity against four cancer cell lines (HepG2, HCT-116, MCF-7, and A431) with IC50s of 13.02 μM, 10.14 μM, 12.68 μM, and 47.05 μM, respectively.

Product Specifications

CAS Number

345615-74-9

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Smiles

OC1=CC=C (NC2=NC=NC3=C2C2=C (CCCC2) S3) C=C1

Molecular Formula

C16H15N3OS

Molecular Weight

297.38

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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