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BMS-684

BMS-684 is a selective DGKα inhibitor with an IC50 of 15 nM. BMS-684 inhibits DGKα kinase activity with >100-fold selectivity over the related DGK type I family members DGKβ and DGKγ. BMS-684 does not inhibit any of the other seven DGK isozymes.

Product Specifications

CAS Number

313552-29-3

Purity

>98% (HPLC)

Smiles

O=C1C ([N+] ([O-]) =O) =C (N2CCN (C (C3=CC=CC=C3) C4=CC=CC=C4) CC2) C5=C (N1C) C=CC=C5

Molecular Formula

C27H26N4O3

Molecular Weight

454.52

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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