ROS-generating?agent?1
ROS-generating agent 1 (Compound 2c) covalently modifies the Sec-498 residue of TrxR to generate ROS. ROS-generating agent 1 reduces intracellular TrxR protein level. ROS-generating agent 1 results in ROS-dependent apoptosis and ferroptosis of NCI-H460 cells. ROS-generating agent 1 has anti-cancer activities.
Product Specifications
CAS Number
2369030-41-9
Field of Research
Signal Transduction
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 33.33 mg/mL (81.03 mM; Ultrasonic)
Smiles
C (=C\1/C (=O) \C (=C\C2=CC (C (F) (F) F) =CC=C2) \CNC1) \C3=CC (C (F) (F) F) =CC=C3
Molecular Formula
C21H15F6NO
Molecular Weight
411.34
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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