TGFβRI-IN-3
TGFβRI-IN-3 inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology.
Product Specifications
CAS Number
2763602-67-9
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (107.40 mM; Ultrasonic (<60°C)
Smiles
N (C=1C2=C (C=C (C=C2) C3=CC=C (S (C) (=O) =O) C=C3) N=CC1) C=4C=C (N=CC4) C5=CC (C) =CC=C5
Molecular Formula
C28H23N3O2S
Molecular Weight
465.57
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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