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TGFβRI-IN-3

TGFβRI-IN-3 inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology.

Product Specifications

CAS Number

2763602-67-9

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 50 mg/mL (107.40 mM; Ultrasonic (<60°C)

Smiles

N (C=1C2=C (C=C (C=C2) C3=CC=C (S (C) (=O) =O) C=C3) N=CC1) C=4C=C (N=CC4) C5=CC (C) =CC=C5

Molecular Formula

C28H23N3O2S

Molecular Weight

465.57

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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