Carvedilol
Carvedilol (SKF 105517) Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output. In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.
Product Specifications
CAS Number
72956-09-3
Product Name Alternative
Field of Research
Cardiovascular Research, Cell Biology, Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.73% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.92 mM) ; Ethanol:20.3 mg/mL (49.94 mM) ; DMSO:40.6 mg/mL (99.88 mM)
Smiles
COC1=CC=CC=C1OCCNCC (O) COC1=C2C (NC3=C2C=CC=C3) =CC=C1
Molecular Formula
C24H26N2O4
Molecular Weight
406.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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