Hydroxybupropion
Hydroxybupropion, the primary active metabolite of bupropion, functions as a neuronal nicotinic acetylcholine receptor (nAChR) antagonist and inhibits norepinephrine reuptake with an IC50 of 1.7 μM. This small molecule is utilized in neuroscience research for investigating antidepressant mechanisms, nicotine addiction, and receptor pharmacology in both in vitro and in vivo models.
Product Specifications
CAS Number
92264-81-8
Product Name Alternative
6-Hydroxybupropion, Norepinephrine uptake, norepinephrine, nAChR, Hydroxybupropion, Hydroxybupropion, , Hydroxybupropion, (+/-) -, Hydroxybupropione
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
98.61% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.9 mM) ; DMSO:90 mg/mL (351.92 mM)
Smiles
C (C (NC (CO) (C) C) C) (=O) C1=CC (Cl) =CC=C1
Molecular Formula
C13H18ClNO2
Molecular Weight
255.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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