IL-22R alpha 1, Canine (HEK293, His)

Product Specifications

UNSPSC Description

IL-22R alpha 1 (IL22RA1) Protein is an IL-22 receptor. IL-22R alpha 1 Protein interacts with IL-22 to activate the JAK/STAT cascade thereby inhibits IL-22 mediated promotion of cell proliferation and anti-apoptosis. IL-22R alpha 1 Protein, Canine (HEK293, His) is expressed by HEK 293 cells and has a transmembrane region (M1-The226) with a His tag at the C-terminus[1].

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-22r-alpha-1-protein-canine-hek293-his.html

Purity

97.60

Smiles

AHIAEDTSDL LQYVKFQSSN FENILTWDSG LESAPDVVYS VEYKTYGKKE WLAKEGCQRI TRKSCNLTTE TGNHTEHYYA RVTAVSAGGR SATKMTDRFS SMQQTTIKPP DVTCIPKVRS IQMIVHPTST PIHAEDGHRL TLEDIFQDLF YRLELQVNHT YQMHLGGKQR DYEFIGLSPD TEFLGTITIS VPNFFKESAP YVCRVKTLPD RT

Molecular Weight

Approximately 28-37 kDa

References & Citations

[1]Cui X, et, al. IL22 furthers malignant transformation of rat mesenchymal stem cells, possibly in association with IL22RA1/STAT3 signaling. Oncol Rep. 2019 Apr;41(4):2148-2158.|[2]Kragstrup TW, et, al. The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis. Front Immunol. 2018 Sep 25;9:2226.|[3]Persaud L, et, al. Mechanism of Action and Applications of Interleukin 24 in Immunotherapy. Int J Mol Sci. 2016 Jun 2;17(6):869.